one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity connected with bortezomib, a proteasome inhibitor Utilized in the treatment method of several myeloma. Its synthesis or research is essential for ensuring the purity and basic safety in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor in the synthesis of abiraterone acetate, a drug Employed in the remedy of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-1): A important compound within the synthesis of imatinib, a drug that targets unique different types of cancer, which includes Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats various cancers for example breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their review is significant for optimizing the production course of action and ensuring significant purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is made use of 3-Hydroxy-1-aminoadamantane to treat breast cancer, and these intermediates are linked to its production.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Employed in the remedy of breast most cancers. Numerous intermediates assist in the synthesis of this drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug successful in managing cancers GeMcitabine InterMediate T6 which include ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and small cell lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, that have various programs, which includes antiviral Homes.
Vildagliptin Intermediates: Utilized in the creation of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated with the synthesis of various gluconic acid derivatives, which might be Employed in food stuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate two: A precursor inside the synthesis of canagliflozin, a medication utilised to control variety two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).